Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | ACACA | Q13085 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | GNA11 | P29992 | 2/20 | 0.32 |
| ▸ | GNAQ | P50148 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865707 | 0.94 | ACACB (0.32) | ACACBACACAHRH3GNA11GNAQ | |
| SCHEMBL8866110 | 0.90 | ACACB (0.41) | ACACBACACAHRH3GNA11GNAQ | |
| SCHEMBL8866367 | 0.85 | ACACB (0.43) | ACACBACACATLR2TLR1TTK | |
| SCHEMBL8867167 | 0.84 | ACACB (0.34) | ACACBACACAHRH3GNA11GNAQ | |
| SCHEMBL8866094 | 0.84 | ACACB (0.45) | ACACBACACATTK | |
| SCHEMBL8867512 | 0.82 | GBA1 (0.34) | NPC1RAB9A | |
| SCHEMBL8866617 | 0.82 | ACACB (0.51) | ACACBACACATTK | |
| SCHEMBL8866762 | 0.80 | NPC1 (0.37) | ACACBACACAGNA11GNAQKDM4E | |
| SCHEMBL8865702 | 0.79 | GBA1 (0.42) | ACACBACACAKDM4ETLR2TLR1 | |
| SCHEMBL8865835 | 0.78 | ACACB (0.49) | ACACBACACATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |