Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | ACACA | Q13085 | 5/20 | 0.41 |
| ▸ | GNA11 | P29992 | 2/20 | 0.34 |
| ▸ | GNAQ | P50148 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867167 | 0.94 | ACACB (0.34) | ACACBACACAGNA11GNAQGPR119 | |
| SCHEMBL8866377 | 0.90 | ACACB (0.38) | ACACBACACAGNA11GNAQGPR119 | |
| SCHEMBL8866617 | 0.85 | ACACB (0.51) | ACACBACACATTK | |
| SCHEMBL8865707 | 0.84 | ACACB (0.32) | ACACBACACAGNA11GNAQGPR119 | |
| SCHEMBL8866094 | 0.84 | ACACB (0.45) | ACACBACACATTK | |
| SCHEMBL8865835 | 0.81 | ACACB (0.49) | ACACBACACATTKWDR5 | |
| SCHEMBL8866762 | 0.80 | NPC1 (0.37) | ACACBACACAGNA11GNAQNPC1 | |
| SCHEMBL8866628 | 0.80 | GNA11 (0.37) | ACACBACACAGNA11GNAQGPR119 | |
| SCHEMBL8866062 | 0.79 | ACACB (0.43) | ACACBACACAGPR119TTK | |
| SCHEMBL8867512 | 0.77 | GBA1 (0.34) | NPC1RAB9AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |