Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283018 | 0.88 | GPR119 (0.41) | GPR119MKNK1MKNK2SUV39H2KDM1A | |
| Water SCHEMBL9283601 | 0.88 | GPR119 (0.41) | GPR119MKNK1MKNK2SUV39H2KDM1A | |
| SCHEMBL8866847 | 0.88 | GPR119 (0.45) | TP53THRBGPR119MKNK1MKNK2 | |
| SCHEMBL8866335 | 0.86 | MKNK1 (0.43) | MKNK1MKNK2SUV39H2KDM1AEGLN2 | |
| SCHEMBL8866874 | 0.86 | SUV39H2 (0.44) | TP53THRBSUV39H2ACACB | |
| SCHEMBL8866849 | 0.86 | SUV39H2 (0.44) | TP53THRBSUV39H2ACACB | |
| SCHEMBL8868301 | 0.86 | CETP (0.45) | GPR119MKNK1MKNK2SUV39H2KDM1A | |
| SCHEMBL8865899 | 0.86 | APP (0.46) | TP53THRBGPR119MKNK1MKNK2 | |
| SCHEMBL8866447 | 0.84 | SUV39H2 (0.46) | TP53THRBSUV39H2POLBACACB | |
| SCHEMBL8865946 | 0.84 | CETP (0.40) | MKNK1MKNK2SUV39H2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |