Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866849 | 0.97 | SUV39H2 (0.44) | SUV39H2THRBPRSS1PRSS2PRSS3 | |
| SCHEMBL8866874 | 0.90 | SUV39H2 (0.44) | SUV39H2THRBTP53ABL1RIN1 | |
| SCHEMBL8866928 | 0.89 | THRB (0.42) | SUV39H2THRBPRSS1PRSS2PRSS3 | |
| SCHEMBL9238827 | 0.88 | SUV39H2 (0.45) | SUV39H2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8866605 | 0.87 | THRB (0.42) | THRBPRSS1PRSS2PRSS3TP53 | |
| SCHEMBL9233170 | 0.85 | SUV39H2 (0.43) | SUV39H2THRBPRSS1PRSS2PRSS3 | |
| SCHEMBL8866503 | 0.84 | TP53 (0.42) | SUV39H2THRBTP53ACACBPOLB | |
| Water SCHEMBL9282757 | 0.84 | SUV39H2 (0.42) | SUV39H2THRBPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL8866457 | 0.83 | ITGB3 (0.47) | SUV39H2PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL8865883 | 0.83 | PRSS1 (0.53) | SUV39H2PRSS1PRSS2PRSS3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |