Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866653 | 0.87 | GAA (0.71) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL23291297 | 0.86 | GAA (0.69) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL9798362 | 0.85 | GAA (0.79) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL19242053 | 0.84 | GAA (1.00) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL8867694 | 0.83 | PTPN1 (0.62) | KDM4EKMT2AALDH1A1POLBMAPT | |
| SCHEMBL8254844 | 0.82 | GAA (0.73) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL7087581 | 0.82 | GAA (0.73) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL8867389 | 0.82 | RAB9A (0.72) | GAAMAPK1KDM4EHTTKMT2A | |
| SCHEMBL23928197 | 0.82 | GAA (0.63) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL5754890 | 0.81 | KDM4E (0.71) | GAAMAPK1KDM4EL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |