Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828589 | 0.95 | GAA (0.70) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL19242053 | 0.89 | GAA (1.00) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL8254844 | 0.86 | GAA (0.73) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL7087581 | 0.86 | GAA (0.73) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL8866653 | 0.85 | GAA (0.71) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL8866646 | 0.85 | GAA (0.71) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL1898755 | 0.85 | GAA (0.91) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL23291297 | 0.83 | GAA (0.69) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL19241697 | 0.83 | GAA (0.88) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL5154816 | 0.81 | PTPN1 (0.69) | MAPK1KDM4ELMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4695405-A | Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |