Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.71 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23150414 | 0.84 | DYRK1A (1.00) | DYRK1AHASPIN | |
| SCHEMBL23150385 | 0.83 | DYRK1A (1.00) | DYRK1AHASPIN | |
| SCHEMBL30772963 | 0.83 | DYRK1A (0.60) | DYRK1AHASPINCNR1CNR2PLA2G2A | |
| SCHEMBL20536528 | 0.83 | DYRK1A (0.60) | DYRK1AHASPINCNR1CNR2PLA2G2A | |
| SCHEMBL8867041 | 0.82 | DYRK1A (0.58) | DYRK1AHASPINCNR1CNR2PSEN1 | |
| SCHEMBL21393273 | 0.80 | DYRK1A (1.00) | DYRK1AHASPIN | |
| SCHEMBL8866663 | 0.79 | DYRK1A (0.50) | DYRK1AHASPINCNR1CNR2PLA2G2A | |
| SCHEMBL30712051 | 0.79 | MTNR1A (0.68) | DYRK1APLA2G2A | |
| SCHEMBL13986773 | 0.79 | DYRK1A (0.52) | DYRK1AHASPINCNR1CNR2PSEN1 | |
| Hydrochloric Acid SCHEMBL8757541 | 0.79 | HASPIN (0.69) | DYRK1AHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677328-A | SLEEP DISORDERS; PSYCHOLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-10-14 | — | — | US | disclosed |