Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13843433 | 0.95 | DYRK1A (0.50) | DYRK1ACNR2CNR1PSEN1PSEN2 | |
| SCHEMBL14489607 | 0.91 | MAOA (0.51) | DYRK1ACNR2CNR1BCHEACHE | |
| SCHEMBL13843431 | 0.86 | PLA2G2A (0.49) | DYRK1ACNR2CNR1BCHEACHE | |
| SCHEMBL13843432 | 0.81 | FABP4 (0.57) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8866752 | 0.79 | DYRK1A (0.71) | DYRK1ACNR2CNR1PSEN1PSEN2 | |
| SCHEMBL6859526 | 0.79 | DYRK1A (0.60) | DYRK1ACNR2CNR1PSEN1PSEN2 | |
| SCHEMBL2361501 | 0.75 | HASPIN (0.64) | DYRK1AHASPIN | |
| SCHEMBL8757901 | 0.74 | MTNR1A (0.61) | DYRK1ACNR2CNR1 | |
| SCHEMBL8356367 | 0.72 | MTNR1A (0.44) | BCHEACHE | |
| SCHEMBL600075 | 0.71 | CNR2 (0.72) | CNR2CNR1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459251-B2 | Imaging member | XEROX CORPORATION (US) | 2008-12-02 | — | — | US | disclosed |
| US-20070141491-A1 | Imaging member | XEROX CORPORATION | 2007-06-21 | — | — | US | disclosed |