Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866564 | 0.90 | CHRM4 (0.46) | EGLN1ALDH1A3CHRM4EGLN2 | |
| SCHEMBL8867140 | 0.86 | EGLN2 (0.42) | EGLN1ALDH1A3CHRM4PREPEGLN2 | |
| SCHEMBL8866150 | 0.84 | ALDH1A3 (0.52) | ALDH1A3EGLN2HDAC1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL8866486 | 0.83 | ALDH1A3 (0.51) | ALDH1A3EGLN2HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8866723 | 0.83 | EGLN1 (0.46) | EGLN1CHRM4HDAC1ALDH1A1HPGD | |
| SCHEMBL8867277 | 0.83 | EGLN1 (0.46) | EGLN1CHRM4HDAC1ALDH1A1HPGD | |
| SCHEMBL8866186 | 0.83 | ALDH1A3 (0.43) | ALDH1A3CHRM4EGLN2HDAC1ALDH1A1 | |
| SCHEMBL8866459 | 0.83 | ALDH1A3 (0.43) | ALDH1A3CHRM4EGLN2HDAC1ALDH1A1 | |
| SCHEMBL8866536 | 0.80 | SUV39H2 (0.43) | CHRM4EGLN2 | |
| SCHEMBL8866504 | 0.80 | APP (0.43) | ALDH1A3CHRM4HDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |