Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866536 | 0.92 | SUV39H2 (0.43) | EGLN2CHRM4SUV39H2NOS3NOS1 | |
| SCHEMBL8866397 | 0.87 | ALDH1A1 (0.51) | EGLN2EGLN1TNFALDH1A3KDM4E | |
| SCHEMBL8866770 | 0.86 | EGLN1 (0.47) | EGLN2CHRM4EGLN1PREPALDH1A3 | |
| SCHEMBL8867032 | 0.85 | EGLN2 (0.38) | EGLN2CHRM4SUV39H2ALDH1A3ALDH1A1 | |
| SCHEMBL8866437 | 0.85 | EGLN2 (0.38) | EGLN2CHRM4SUV39H2ALDH1A3ALDH1A1 | |
| SCHEMBL8866164 | 0.85 | SUV39H2 (0.43) | CHRM4SUV39H2PTPRCKDM4ENPC1 | |
| SCHEMBL8866078 | 0.85 | SUV39H2 (0.43) | CHRM4SUV39H2PTPRCKDM4ENPC1 | |
| SCHEMBL8867371 | 0.83 | APP (0.40) | EGLN2CHRM4SUV39H2ALDH1A3KDM4E | |
| SCHEMBL8865926 | 0.83 | SUV39H2 (0.47) | CHRM4SUV39H2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8866254 | 0.82 | APP (0.39) | EGLN2CHRM4SUV39H2ALDH1A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |