Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866095 | 0.92 | KDM4E (0.41) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8866560 | 0.90 | KDM4E (0.41) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8866818 | 0.87 | SMN1; SMN2 (0.36) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8866636 | 0.87 | KDM4E (0.41) | KDM4ENPC1RAB9APOLBTP53 | |
| SCHEMBL8865866 | 0.86 | CYP3A4 (0.46) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8866712 | 0.84 | CYP3A4 (0.46) | KDM4ENPC1RAB9ASUV39H2TP53 | |
| SCHEMBL9235965 | 0.83 | ACACB (0.37) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8866523 | 0.82 | RAB9A (0.43) | SUCNR1NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL8867530 | 0.80 | ADORA3 (0.43) | SUCNR1KDM4ENPC1RAB9APOLB | |
| SCHEMBL8866926 | 0.79 | CYP3A4 (0.47) | SUCNR1KDM4EACACBACACAALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |