Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866090 | 0.76 | GPR119 (0.47) | LMNAGAAGPR119EGFRALDH1A1 | |
| SCHEMBL19575152 | 0.75 | HDAC2 (0.42) | LMNAGAAGPR119EGFRALDH1A1 | |
| SCHEMBL8865871 | 0.73 | ALDH1A1 (0.42) | LMNAGAAGPR119EGFRALDH1A1 | |
| SCHEMBL19570399 | 0.69 | GAA (0.33) | LMNAGAAGPR119EGFRALDH1A1 | |
| SCHEMBL10815443 | 0.66 | PDE3B (0.52) | LMNAGAAGPR119ALDH1A1MEN1 | |
| SCHEMBL11754295 | 0.65 | PDE4A (0.51) | LMNAGAAGPR119ALDH1A1MEN1 | |
| SCHEMBL11529134 | 0.65 | PDE4A (0.51) | LMNAGAAGPR119ALDH1A1MEN1 | |
| SCHEMBL11365384 | 0.65 | HRH3 (0.51) | GAAGPR119NPSR1HTT | |
| SCHEMBL11754286 | 0.65 | PDE4A (0.51) | LMNAGAAGPR119ALDH1A1MEN1 | |
| SCHEMBL11754282 | 0.65 | PDE4A (0.51) | LMNAGAAGPR119ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639776-A | CROP PESTICIDE; NONPHYTOTOXIC, KIDNEY BEANS, ORANGES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-17 | — | — | US | disclosed |