Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 9/20 | 0.45 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866298 | 0.91 | SUV39H2 (0.52) | SUV39H2NAMPTALDH1A1CHRM4 | |
| SCHEMBL8866633 | 0.89 | NR4A2 (0.43) | SUV39H2NAMPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8866417 | 0.87 | ALDH1A1 (0.46) | SUV39H2NAMPTALDH1A1HPGDMAPK1 | |
| SCHEMBL8867143 | 0.82 | ALDH1A1 (0.41) | SUV39H2ALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL8867006 | 0.79 | KDM4E (0.42) | SUV39H2ALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL8867482 | 0.79 | SUV39H2 (0.47) | SUV39H2ALDH1A1HPGD | |
| SCHEMBL8866643 | 0.79 | SUV39H2 (0.47) | SUV39H2NAMPTALDH1A1HPGD | |
| SCHEMBL8867188 | 0.79 | SUV39H2 (0.44) | SUV39H2NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9229599 | 0.78 | SUV39H2 (0.45) | SUV39H2ALDH1A1HPGDCHRM4 | |
| SCHEMBL8866536 | 0.77 | SUV39H2 (0.43) | SUV39H2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |