Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866307 | 0.92 | SUV39H2 (0.46) | ALDH1A1SUV39H2RAB9AKDM4ENPC1 | |
| SCHEMBL8866648 | 0.90 | NR4A2 (0.42) | ALDH1A1SMN1; SMN2HPGDMAPK1GFER | |
| SCHEMBL8866424 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDMAPK1SUV39H2 | |
| SCHEMBL8867134 | 0.82 | SUV39H2 (0.45) | ALDH1A1SMN1; SMN2HPGDMAPK1SUV39H2 | |
| SCHEMBL8867199 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDSUV39H2RAB9A | |
| SCHEMBL8866283 | 0.78 | SUV39H2 (0.45) | ALDH1A1SMN1; SMN2HPGDSUV39H2RAB9A | |
| SCHEMBL8866134 | 0.78 | SUV39H2 (0.45) | ALDH1A1SMN1; SMN2HPGDSUV39H2RAB9A | |
| SCHEMBL8866652 | 0.76 | SUV39H2 (0.45) | ALDH1A1SMN1; SMN2SUV39H2RAB9AKDM4E | |
| SCHEMBL8866633 | 0.76 | NR4A2 (0.43) | ALDH1A1SMN1; SMN2HPGDSUV39H2RAB9A | |
| SCHEMBL8866791 | 0.76 | SUV39H2 (0.47) | ALDH1A1SMN1; SMN2HPGDMAPK1SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |