Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868337 | 0.88 | RAB9A (0.74) | TARBP2PPARDRAB9AKDM4EGAA | |
| SCHEMBL3436647 | 0.86 | RAB9A (0.77) | TARBP2RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL8868002 | 0.84 | RAB9A (0.54) | TARBP2FFAR1PPARDRAB9AKDM4E | |
| SCHEMBL8867803 | 0.81 | TARBP2 (0.73) | TARBP2FFAR1PPARDRAB9AKDM4E | |
| SCHEMBL15048965 | 0.80 | TRPM8 (0.80) | FFAR1PPARDKDM4EMAOBTRPM8 | |
| SCHEMBL3419091 | 0.79 | RAB9A (0.74) | TARBP2RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL28412421 | 0.79 | TARBP2 (1.00) | TARBP2PPARDRAB9AKDM4EGAA | |
| SCHEMBL3071111 | 0.79 | TARBP2 (0.70) | TARBP2PPARDRAB9AKDM4EGAA | |
| SCHEMBL8867253 | 0.77 | TARBP2 (0.67) | TARBP2FFAR1PPARDRAB9AKDM4E | |
| SCHEMBL8339610 | 0.77 | TARBP2 (0.66) | TARBP2PPARDRAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |