Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866254 | 0.91 | APP (0.39) | APPCHRM4GPR119TLR9TLR7 | |
| SCHEMBL8866419 | 0.87 | APP (0.44) | APPCHRM4TLR9TLR7ALDH1A3 | |
| SCHEMBL8867140 | 0.83 | EGLN2 (0.42) | CHRM4ALDH1A3NPC1RAB9AKDM4E | |
| SCHEMBL8866504 | 0.81 | APP (0.43) | APPCHRM4TLR9TLR7ALDH1A3 | |
| SCHEMBL8866536 | 0.81 | SUV39H2 (0.43) | CHRM4SUV39H2EGLN2 | |
| SCHEMBL8865946 | 0.79 | CETP (0.40) | CHRM4SUV39H2EGLN2HRH3 | |
| SCHEMBL8867032 | 0.78 | EGLN2 (0.38) | CHRM4ALDH1A3SMN1; SMN2ALDH1A1SUV39H2 | |
| SCHEMBL8866437 | 0.78 | EGLN2 (0.38) | CHRM4ALDH1A3SMN1; SMN2ALDH1A1SUV39H2 | |
| SCHEMBL8865989 | 0.78 | SUV39H2 (0.41) | CHRM4TLR9TLR7SUV39H2EGLN2 | |
| SCHEMBL8868301 | 0.76 | CETP (0.45) | GPR119SUV39H2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |