Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866437 | 1.00 | EGLN2 (0.38) | EGLN2ALDH1A3XDHFFAR1SUV39H2 | |
| SCHEMBL8867140 | 0.85 | EGLN2 (0.42) | EGLN2ALDH1A3SUV39H2CHRM4ALDH1A1 | |
| SCHEMBL8866536 | 0.83 | SUV39H2 (0.43) | EGLN2SUV39H2CHRM4 | |
| SCHEMBL8866459 | 0.81 | ALDH1A3 (0.43) | EGLN2ALDH1A3FFAR1CHRM4ALDH1A1 | |
| SCHEMBL8866186 | 0.81 | ALDH1A3 (0.43) | EGLN2ALDH1A3FFAR1CHRM4ALDH1A1 | |
| SCHEMBL8867371 | 0.78 | APP (0.40) | EGLN2ALDH1A3SUV39H2CHRM4ALDH1A1 | |
| SCHEMBL8866254 | 0.77 | APP (0.39) | EGLN2ALDH1A3SUV39H2CHRM4ALDH1A1 | |
| SCHEMBL8865946 | 0.76 | CETP (0.40) | EGLN2SUV39H2CHRM4 | |
| SCHEMBL8867524 | 0.74 | ALDH1A1 (0.47) | EGLN2ALDH1A3XDHALDH1A1SMN1; SMN2 | |
| SCHEMBL8865989 | 0.74 | SUV39H2 (0.41) | EGLN2SUV39H2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |