Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31657672 | 0.84 | PARP1 (0.45) | KDM4ETDP1ALDH1A1MAPTNAPRT | |
| SCHEMBL17141443 | 0.84 | PARP1 (0.45) | KDM4ETDP1ALDH1A1MAPTNAPRT | |
| SCHEMBL8867445 | 0.83 | KDM4E (0.42) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL28046952 | 0.80 | PRKCI (0.55) | KDM4ETDP1ALDH1A1NPSR1CYP3A4 | |
| SCHEMBL8867005 | 0.79 | TSHR (0.49) | KDM4EALDH1A1L3MBTL1TSHRLMNA | |
| SCHEMBL270419 | 0.77 | KDM4E (1.00) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL30639802 | 0.75 | KDM4E (0.95) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL30639818 | 0.75 | KDM4E (0.95) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL29723448 | 0.75 | KDM4E (0.95) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL7360367 | 0.75 | KDM4E (0.61) | KDM4ETDP1ALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670456-A | Compounds | SANDOZ LTD. (CH) | 1997-09-23 | — | — | US | disclosed |
| US-5506191-A | Heterocyclic hydrazines and hydrazones | SANDOZ LTD. (CH) | 1996-04-09 | — | — | US | disclosed |