SCHEMBL8867439

SCHEMBL8867439

COc1ccc(C[C@@H](C)NCCc2ccccc2)cc1OC

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 13/20 0.70
KCNH2 Q12809 1/20 0.57
SLC2A1 P11166 2/20 0.55
KDM1A O60341 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8868043 0.99 SIGMAR1 (0.72) SIGMAR1KCNH2SLC2A1KDM1A
SCHEMBL6094958 0.94 SIGMAR1 (0.65) SIGMAR1KCNH2SLC2A1
SCHEMBL6093694 0.94 SIGMAR1 (0.65) SIGMAR1KCNH2SLC2A1
SCHEMBL19505484 0.92 SIGMAR1 (0.70) SIGMAR1
SCHEMBL19505494 0.91 SIGMAR1 (0.68) SIGMAR1
SCHEMBL7929023 0.86 SIGMAR1 (0.63) SIGMAR1KDM1A
SCHEMBL7929020 0.86 SIGMAR1 (0.63) SIGMAR1KDM1A
SCHEMBL6135925 0.83 ADRA1D (0.73) SIGMAR1KCNH2SLC2A1
SCHEMBL6135926 0.83 ADRA1D (0.73) SIGMAR1KCNH2SLC2A1
SCHEMBL4015652 0.83 ADRA1D (0.58) SIGMAR1KCNH2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663360-A REACTING 3,4-DIMETHOXYAMPHETAMINE WITH 3-CHLOROMANDELIC ACID F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 1997-09-02 US claimed
US-5663360-A REACTING 3,4-DIMETHOXYAMPHETAMINE WITH 3-CHLOROMANDELIC ACID F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 1997-09-02 US disclosed