Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867003 | 0.87 | SMN1; SMN2 (0.57) | ALDH1A1TDP1LMNACYP1A2CYP2C19 | |
| SCHEMBL18138414 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL8867665 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL10410570 | 0.86 | KDM4E (0.60) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL30875697 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL1531355 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL19122730 | 0.83 | PPARG (0.55) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL28739225 | 0.83 | MAPT (0.47) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL704754 | 0.82 | TTR (0.64) | ALDH1A1TDP1LMNAMAPTCYP1A2 | |
| SCHEMBL14136128 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |