Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867665 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL8867007 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2TTRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29750606 | 0.87 | TTR (0.64) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL704754 | 0.87 | TTR (0.64) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL8867650 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL10410570 | 0.84 | KDM4E (0.60) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL9384459 | 0.84 | KCNH2 (0.49) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 | |
| SCHEMBL9384240 | 0.84 | MAPT (0.50) | SMN1; SMN2TTRMAPTCYP1A2CYP3A4 | |
| SCHEMBL2030062 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2TTRMAPTCYP1A2CYP3A4 | |
| SCHEMBL1531355 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2TTRCHEK1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |