Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867721 | 0.83 | TDP1 (0.50) | FFAR1FFAR4CA12CA1CA2 | |
| SCHEMBL20715471 | 0.83 | SIGMAR1 (0.39) | CA2 | |
| SCHEMBL5549485 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDALOX15ALOX12HSD17B10 | |
| SCHEMBL1837 | 0.70 | — | — | |
| SCHEMBL8868648 | 0.68 | SMN1; SMN2 (0.63) | MAPTHTTMEN1KMT2A | |
| SCHEMBL18773979 | 0.68 | TP53 (0.42) | HPGDHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10540891 | 0.67 | GFER (0.42) | FFAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL23554965 | 0.67 | HPGD (0.48) | ALDH1A1HPGDALOX12CA12CA1 | |
| SCHEMBL11762144 | 0.67 | MAPT (0.48) | ALDH1A1HPGDALOX15ALOX12HSD17B10 | |
| SCHEMBL22112759 | 0.67 | FFAR4 (0.32) | FFAR4ALDH1A1ALOX15ALOX12CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |