Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869152 | 0.91 | EGLN1 (0.54) | P4HTMEGFREGLN1FLT1FLT4 | |
| SCHEMBL8869167 | 0.90 | P4HTM (0.54) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL9137569 | 0.90 | P4HTM (0.54) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8868721 | 0.90 | P4HTM (0.48) | P4HTMEGFREGLN1FLT1FLT4 | |
| SCHEMBL8869146 | 0.89 | P4HTM (0.44) | P4HTMEGFREGLN1FLT1FLT4 | |
| SCHEMBL8870235 | 0.89 | EGLN1 (0.50) | P4HTMEGFREGLN1 | |
| SCHEMBL8868726 | 0.88 | P4HTM (0.50) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8869164 | 0.88 | P4HTM (0.50) | P4HTMCA12CA9 | |
| SCHEMBL8868080 | 0.88 | EGLN1 (0.47) | P4HTMEGFREGLN1POLB | |
| SCHEMBL8868842 | 0.86 | P4HTM (0.48) | P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |