Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870235 | 0.96 | EGLN1 (0.50) | EGLN1P4HTMCYP2C9CYP2C19EGFR | |
| SCHEMBL8868080 | 0.91 | EGLN1 (0.47) | EGLN1P4HTMEGFRALDH1A1LMNA | |
| SCHEMBL8867730 | 0.91 | P4HTM (0.48) | EGLN1P4HTMEGFRFLT1FLT4 | |
| SCHEMBL8868634 | 0.91 | P4HTM (0.51) | EGLN1P4HTMCYP2C9EGFRCA2 | |
| SCHEMBL9139559 | 0.91 | P4HTM (0.50) | EGLN1P4HTMCYP2C9CYP2C19EGFR | |
| SCHEMBL8868721 | 0.90 | P4HTM (0.48) | EGLN1P4HTMEGFRFLT1FLT4 | |
| SCHEMBL8869146 | 0.89 | P4HTM (0.44) | EGLN1P4HTMEGFRCA2ALDH1A1 | |
| SCHEMBL8868007 | 0.89 | P4HTM (0.47) | EGLN1P4HTMCYP2C9EGFRCA2 | |
| SCHEMBL8869206 | 0.89 | P4HTM (0.47) | EGLN1P4HTMNPC1RAB9A | |
| SCHEMBL8869147 | 0.88 | P4HTM (0.46) | EGLN1P4HTMCYP2C9EGFRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |