Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868726 | 0.92 | P4HTM (0.50) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8867726 | 0.90 | P4HTM (0.48) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8867730 | 0.90 | P4HTM (0.48) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8868634 | 0.90 | P4HTM (0.51) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8869204 | 0.90 | P4HTM (0.53) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8869227 | 0.89 | P4HTM (0.55) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8868272 | 0.89 | P4HTM (0.48) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8868467 | 0.88 | P4HTM (0.71) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL8868794 | 0.88 | CA2 (0.50) | P4HTMEGFRKDM4EMEN1KMT2A | |
| SCHEMBL8869447 | 0.88 | P4HTM (0.49) | P4HTMEGFRFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |