Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867826 | 0.91 | P4HTM (0.39) | P4HTMCXCR1CXCR2PRKAA2KMT2A | |
| SCHEMBL8869554 | 0.91 | P4HTM (0.51) | P4HTMPRKAA2SMN1; SMN2 | |
| SCHEMBL8870184 | 0.90 | KMT2A (0.46) | P4HTMPRKAA2KMT2APOLB | |
| SCHEMBL9139374 | 0.88 | P4HTM (0.44) | P4HTMCXCR1CXCR2CYP4F2CYP4A11 | |
| SCHEMBL8869725 | 0.88 | P4HTM (0.39) | P4HTMCXCR1CXCR2PRKAA2KMT2A | |
| SCHEMBL8869623 | 0.85 | P4HTM (0.49) | P4HTMSMN1; SMN2 | |
| SCHEMBL8867860 | 0.84 | P4HTM (0.48) | P4HTMPRKAA2SMN1; SMN2 | |
| SCHEMBL8869129 | 0.84 | MAPT (0.49) | P4HTMKMT2ASMN1; SMN2 | |
| SCHEMBL8868676 | 0.84 | MAPT (0.49) | P4HTMKMT2ASMN1; SMN2 | |
| SCHEMBL8867821 | 0.84 | CXCR1 (0.40) | P4HTMCXCR1CXCR2PRKAA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |