Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869429 | 0.94 | P4HTM (0.53) | P4HTMKMT2ACXCR2CXCR1BCL2L1 | |
| SCHEMBL8869569 | 0.90 | P4HTM (0.48) | P4HTMKMT2ACXCR2CXCR1PRKAA2 | |
| SCHEMBL8869722 | 0.88 | CXCR1 (0.44) | P4HTMKMT2ACXCR2CXCR1PRKAA2 | |
| SCHEMBL8869383 | 0.86 | P4HTM (0.46) | P4HTMPRKAA2ALDH1A1 | |
| SCHEMBL8868011 | 0.85 | P4HTM (0.53) | P4HTMKMT2ACXCR2CXCR1SMN1; SMN2 | |
| SCHEMBL8869957 | 0.85 | P4HTM (0.67) | P4HTMKMT2ACXCR2CXCR1SMN1; SMN2 | |
| SCHEMBL8868598 | 0.84 | P4HTM (0.51) | P4HTMKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL8869725 | 0.83 | P4HTM (0.39) | P4HTMKMT2ACXCR2CXCR1PRKAA2 | |
| SCHEMBL8868409 | 0.83 | P4HTM (0.50) | P4HTMKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL8869544 | 0.83 | ALDH1A1 (0.49) | P4HTMKMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |