Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867854 | 0.84 | RAB9A (0.72) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867598 | 0.84 | KDM4E (0.67) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867336 | 0.82 | CDC7 (0.62) | KDM4EALDH1A1MAPT | |
| SCHEMBL8866977 | 0.81 | XDH (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8868246 | 0.79 | KDM4E (0.60) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL2069278 | 0.78 | RAB9A (1.00) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8869083 | 0.78 | TARBP2 (0.65) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL892234 | 0.78 | RAB9A (1.00) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL23794689 | 0.77 | KMT2A (0.80) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL12725600 | 0.77 | RAB9A (0.65) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |