Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200687 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL844745 | 0.83 | TSHR (0.59) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL16616136 | 0.83 | TSHR (0.51) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28066682 | 0.83 | TSHR (0.51) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL1542171 | 0.82 | TSHR (0.58) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL29570791 | 0.82 | TSHR (0.58) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL6417736 | 0.82 | L3MBTL1 (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL8126448 | 0.82 | TSHR (0.50) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15131223 | 0.81 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL4034951 | 0.81 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670456-A | Compounds | SANDOZ LTD. (CH) | 1997-09-23 | — | — | US | disclosed |