Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542171 | 0.89 | TSHR (0.58) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL29570791 | 0.89 | TSHR (0.58) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4720596 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| Bromide SCHEMBL16541033 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL8200687 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15131223 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL4034951 | 0.87 | TSHR (0.56) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL10515633 | 0.86 | MAPT (0.60) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL22912514 | 0.86 | TSHR (0.54) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4719925 | 0.86 | TSHR (0.54) | TSHRHTTALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117547534-B | Nicorandil sustained release preparation and preparation method thereof | 江南大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-117618376-A | Nicorandil membrane controlled slow release tablet and preparation method thereof | 江苏诺和必拓新药研发有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117547534-A | Nicorandil sustained release preparation and preparation method thereof | 江苏诺和必拓新药研发有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-113518610-A | Composition for lightening or whitening keratin materials | 莱雅公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-113438938-A | Composition for lightening or whitening keratin materials | 莱雅公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-113226253-A | Composition for lightening or whitening keratin materials | 莱雅公司 | 2021-08-06 | — | — | CN | disclosed |
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-17 | — | — | US | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| US-9315521-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITé LAVAL (CA) | 2016-04-19 | — | — | US | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| US-7723367-B2 | Amino-tetrazoles analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-05-25 | — | — | US | disclosed |
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | ABBOTT LABORATORIES (US) | 2008-07-17 | — | — | US | disclosed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | disclosed |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | ABBVIE INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | disclosed |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | ABBVIE INC. | 2006-03-09 | — | — | US | disclosed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | TSHR 4661/4885HTT 4119/4885ALDH1A1 577/4885 |
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | P2RX7, P2RX2, P2RX5 | TSHR 543/4885HTT 3101/4885ALDH1A1 3041/4885 |
| US-20080146569-A1 | Nicotinamide Derivatives | NNT, NAMPT, NADK | TSHR 3944/4885HTT 3053/4885ALDH1A1 148/4885 |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | P2RX7, P2RX2, P2RX5 | TSHR 543/4885HTT 3101/4885ALDH1A1 3041/4885 |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | P2RX7, P2RX2, P2RX3 | TSHR 513/4885HTT 3134/4885ALDH1A1 3045/4885 |
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | MPI, MAG, MNS1 | TSHR 1163/4885HTT 2841/4885ALDH1A1 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.