Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | CDC7 | O00311 | 9/20 | 0.69 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049004 | 0.84 | TRPM8 (1.00) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL8867840 | 0.83 | CDC7 (0.57) | TRPM8MAPTCDC7DBF4KMT2A | |
| SCHEMBL15048955 | 0.82 | TRPM8 (1.00) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL15049060 | 0.82 | TRPM8 (0.80) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL15049096 | 0.82 | TRPM8 (1.00) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL6338322 | 0.82 | TRPM8 (1.00) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL27997098 | 0.81 | TRPM8 (0.78) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL5240574 | 0.81 | CDC7 (1.00) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL15048995 | 0.80 | TRPM8 (0.76) | TRPM8MAPTCDC7DBF4MEN1 | |
| SCHEMBL15048965 | 0.78 | TRPM8 (0.80) | TRPM8MAPTCDC7DBF4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |