Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868176 | 0.93 | P4HTM (0.53) | P4HTMSCN9ASCN10AALDH1A1HPGD | |
| SCHEMBL8869196 | 0.91 | P4HTM (0.53) | P4HTMSCN9AALDH1A1HPGDCYP1A2 | |
| SCHEMBL8869132 | 0.89 | P4HTM (0.51) | P4HTMSCN9AALDH1A1HPGDCYP1A2 | |
| SCHEMBL8870003 | 0.89 | P4HTM (0.56) | P4HTMALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL8869962 | 0.87 | P4HTM (0.58) | P4HTMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7870444 | 0.86 | P4HTM (0.46) | P4HTMSCN9ASCN10AALDH1A1HPGD | |
| SCHEMBL8867785 | 0.86 | ALKBH2 (0.52) | P4HTMSCN9ASCN10AALDH1A1HPGD | |
| SCHEMBL8867662 | 0.85 | SCN9A (0.48) | SCN9ASCN10AALDH1A1HPGDCYP1A2 | |
| SCHEMBL8870069 | 0.84 | P4HTM (0.57) | P4HTMSCN9ASCN10ACYP1A2CYP2C9 | |
| SCHEMBL8868915 | 0.84 | P4HTM (0.66) | P4HTMALDH1A1HPGDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |