SCHEMBL8868375

SCHEMBL8868375

N#Cc1ccc(C(=O)Nc2ccc(CCO)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.59
NAMPT P43490 2/20 0.56
SAE1 Q9UBE0 1/20 0.55
UBA2 Q9UBT2 1/20 0.55
MEN1 O00255 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
KMT2A Q03164 1/20 0.55
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
CNR1 P21554 1/20 0.51
ESR1 P03372 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
ROCK2 O75116 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
DPP4 P27487 1/20 0.48
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8868369 0.88 MLYCD (0.59) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL9337665 0.86 MLYCD (0.76) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL6263516 0.86 MLYCD (0.76) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL2896501 0.84 MLYCD (0.61) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL9238331 0.82 MLYCD (0.53) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL14191199 0.82 NAMPT (0.60) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL2830292 0.81 MLYCD (0.66) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL22523739 0.81 MLYCD (0.62) MLYCDNAMPTSAE1UBA2MEN1
SCHEMBL8867655 0.80 PTPN1 (0.65) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL8867052 0.80 POLB (0.71) MEN1NPC1RAB9AKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686484-A ANTHELMINTICS, ACARICIDES, INSECTICIDES SANKYO CO., LTD. (JP) 1997-11-11 US disclosed