Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253364 | 0.88 | CYP11B1 (0.52) | MAPTCYP11B1CYP11B2RAB9APOLB | |
| SCHEMBL9237156 | 0.87 | KMT2A (0.57) | SMN1; SMN2NR1H4MAPTLMNANPC1 | |
| SCHEMBL1338556 | 0.86 | CYP11B1 (0.60) | SMN1; SMN2MAPTCYP11B1CYP11B2NPC1 | |
| SCHEMBL8988613 | 0.85 | RORC (0.55) | SMN1; SMN2MAPTLMNACYP11B1CYP11B2 | |
| SCHEMBL9267010 | 0.85 | RAB9A (0.62) | SMN1; SMN2MAPTCYP11B1CYP11B2NPC1 | |
| SCHEMBL9237286 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NR1H4MAPTLMNANPC1 | |
| SCHEMBL8519675 | 0.83 | RAB9A (0.52) | NR1H4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL9264988 | 0.82 | EPHX2 (0.49) | MAPTCYP11B1CYP11B2RAB9APOLB | |
| SCHEMBL8868369 | 0.82 | MLYCD (0.59) | MLYCDMAPTNAMPTCYP11B1CYP11B2 | |
| SCHEMBL8868375 | 0.82 | MLYCD (0.59) | MLYCDMAPTNAMPTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |