Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 9/20 | 0.63 |
| ▸ | HTR1D | P28221 | 4/20 | 0.63 |
| ▸ | HTR1B | P28222 | 3/20 | 0.63 |
| ▸ | HTR2C | P28335 | 7/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR5A | P47898 | 2/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | HTR1F | P30939 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868836 | 0.94 | HTR1A (0.71) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| Oxalic Acid SCHEMBL10569544 | 0.82 | KMT2A (0.63) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL9805227 | 0.81 | HTR1D (0.67) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| Oxalic Acid SCHEMBL10566895 | 0.81 | KMT2A (0.53) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| Bufotenine SCHEMBL5832731 | 0.81 | HTR1A (0.86) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| Oxalic Acid SCHEMBL9800389 | 0.81 | HTR1A (0.72) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| Oxalic Acid SCHEMBL8900028 | 0.81 | HTR1A (0.88) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| Oxalic Acid SCHEMBL10693634 | 0.81 | HTR1A (0.57) | KMT2AHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL12018386 | 0.81 | HTR1D (0.72) | HTR1AHTR1DHTR1BHTR2CHTR2A | |
| Oxalic Acid SCHEMBL9800367 | 0.81 | KMT2A (0.60) | KMT2AHTR1AHTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637593-A | MIGRAINE; HYPOTENSIVE AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |