Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868956 | 0.95 | TSHR (0.53) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8868086 | 0.92 | TSHR (0.54) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8869492 | 0.90 | CA1 (0.53) | MEN1KMT2ATSHRALDH1A1CA1 | |
| SCHEMBL8868124 | 0.90 | TSHR (0.58) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8869545 | 0.87 | CA1 (0.54) | MEN1KMT2ATSHRALDH1A1CA1 | |
| SCHEMBL8868966 | 0.87 | TSHR (0.58) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8869757 | 0.87 | TSHR (0.60) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8868437 | 0.87 | TSHR (0.52) | CNR2KMT2ATSHRALDH1A1CA1 | |
| SCHEMBL8868963 | 0.86 | TSHR (0.54) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8868857 | 0.86 | TSHR (0.61) | CNR2MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |