Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870177 | 0.94 | KMT2A (0.46) | KMT2AMEN1P4HTMPOLBMMP8 | |
| SCHEMBL8867821 | 0.91 | CXCR1 (0.40) | KMT2AMEN1P4HTMPOLBCNR2 | |
| SCHEMBL8869544 | 0.85 | ALDH1A1 (0.49) | KMT2AMEN1P4HTMMMP8MMP12 | |
| SCHEMBL8868434 | 0.84 | KMT2A (0.45) | KMT2AMEN1P4HTMPOLBMMP8 | |
| SCHEMBL8870184 | 0.84 | KMT2A (0.46) | KMT2AMEN1P4HTMPOLBMMP8 | |
| SCHEMBL8869549 | 0.84 | P4HTM (0.50) | KMT2AMEN1P4HTMPOLBMMP8 | |
| SCHEMBL8869086 | 0.83 | P4HTM (0.45) | P4HTMPOLBMMP1TP53 | |
| SCHEMBL8869538 | 0.83 | KMT2A (0.55) | KMT2AMEN1P4HTMPOLBMMP8 | |
| SCHEMBL9140185 | 0.82 | P4HTM (0.48) | KMT2AMEN1P4HTMMMP8MMP12 | |
| SCHEMBL8869643 | 0.82 | KMT2A (0.56) | KMT2AMEN1P4HTMPOLBMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |