Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869213 | 0.91 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL9140271 | 0.91 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8868721 | 0.90 | P4HTM (0.48) | P4HTMHPGDEGLN1 | |
| SCHEMBL8868842 | 0.89 | P4HTM (0.48) | RAB9ANPC1SMN1; SMN2P4HTM | |
| SCHEMBL8869880 | 0.89 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8868602 | 0.89 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8869726 | 0.89 | P4HTM (0.54) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8868754 | 0.88 | PPARA (0.48) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8869146 | 0.88 | P4HTM (0.44) | RAB9ANPC1SMN1; SMN2P4HTMPOLB | |
| SCHEMBL8869343 | 0.88 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2P4HTMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |