Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869654 | 0.92 | P4HTM (0.51) | P4HTMSCN3AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8869289 | 0.91 | HTT (0.53) | P4HTML3MBTL1ALDH1A1LMNAHPGDS | |
| SCHEMBL8869164 | 0.91 | P4HTM (0.50) | P4HTMSCN3AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8869203 | 0.91 | P4HTM (0.52) | P4HTMSCN3AL3MBTL1LMNACA2 | |
| SCHEMBL8869158 | 0.90 | P4HTM (0.49) | P4HTMSCN3AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8869868 | 0.90 | P4HTM (0.66) | P4HTMALDH1A1 | |
| SCHEMBL8868562 | 0.90 | P4HTM (0.51) | P4HTMNAMPT | |
| SCHEMBL8868326 | 0.89 | P4HTM (0.50) | P4HTMEPHX2NAMPT | |
| SCHEMBL8869822 | 0.89 | P4HTM (0.54) | P4HTMSCN3AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8870171 | 0.88 | P4HTM (0.49) | P4HTMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |