Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869962 | 0.91 | P4HTM (0.58) | P4HTMALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8870098 | 0.91 | RAB9A (0.54) | P4HTML3MBTL1LMNAALDH1A1HPGD | |
| SCHEMBL8868861 | 0.91 | P4HTM (0.52) | P4HTMHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8868915 | 0.90 | P4HTM (0.66) | P4HTMALDH1A1CA2HPGD | |
| SCHEMBL8867998 | 0.90 | P4HTM (0.51) | P4HTMHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8868425 | 0.90 | P4HTM (0.53) | P4HTMLMNAALDH1A1HPGDNPC1 | |
| SCHEMBL8868641 | 0.89 | P4HTM (0.54) | P4HTMSCN3AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8868295 | 0.87 | P4HTM (0.48) | P4HTMHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8867816 | 0.87 | P4HTM (0.53) | P4HTMCA2HPGDNPC1RAB9A | |
| SCHEMBL8868113 | 0.87 | P4HTM (0.67) | P4HTML3MBTL1ALDH1A1HPGDHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |