Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 10/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868641 | 0.90 | P4HTM (0.54) | P4HTMALDH1A1 | |
| SCHEMBL8868467 | 0.89 | P4HTM (0.71) | P4HTMEGFRKDM4EMEN1KMT2A | |
| SCHEMBL8868172 | 0.88 | P4HTM (0.72) | P4HTMPTGS2PTGS1EGFRKDM4E | |
| SCHEMBL8869167 | 0.88 | P4HTM (0.54) | P4HTMPTGS2PTGS1EGFRKDM4E | |
| SCHEMBL8868236 | 0.87 | P4HTM (0.51) | P4HTMNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL8869213 | 0.87 | RAB9A (0.53) | P4HTMNPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8868562 | 0.87 | P4HTM (0.51) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8869289 | 0.87 | HTT (0.53) | P4HTMALDH1A1RAB9A | |
| SCHEMBL8868326 | 0.87 | P4HTM (0.50) | P4HTMNPC1RAB9AKMT2A | |
| SCHEMBL8868915 | 0.86 | P4HTM (0.66) | P4HTMPTGS2PTGS1EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |