Acetone

Acetone

SCHEMBL886877

C=CC(=O)NC=O.CC(C)=O.CC(C)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
TSHR P16473 5/20 0.42
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TGM2 P21980 6/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
LMNA P02545 3/20 0.32
TP53 P04637 1/20 0.32
FGFR4 P22455 1/20 0.30
F13A1 P00488 1/20 0.30
TGM1 P22735 1/20 0.30
TGM3 Q08188 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246479 0.92
Bromide SCHEMBL11652645 0.89
Propylene Glycol SCHEMBL10879884 0.78 TSHR (0.43) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL9850665 0.74
Acetone SCHEMBL11851548 0.73 TSHR (0.38) ALDH1A1TSHRMAPK1TDP1TGM2
Acetone SCHEMBL5416010 0.72 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1TDP1TGM2
SCHEMBL10457889 0.72
SCHEMBL1928090 0.72
SCHEMBL31757163 0.72 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1TDP1TGM2
Acetone SCHEMBL5921885 0.72 LMNA (0.38) ALDH1A1TSHRMAPK1TDP1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4112036-A THERMOSETTING POLYESTER RESINS CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1978-09-05 US claimed
EP-1646697-B1 ADHESIVE COMPOSITION FOR THE MANUFACTURING OF CORRUGATED PAPER BOARD CORRUTECH (BE) 2012-01-11 EP disclosed
US-6375775-B2 A WATER-RESISTANT, VISCOSITY STABLE, ALKALINE CURING, STARCH-BASED CORRUGATING ADHESIVE COMPRISING STARCH, AN ALKALI MATERIAL, A KETONE-FORMALDEHYDE CROSSLINKING ADDITIVE CONTAINING SULFITE SALTS WITH REDUCED FREE ALDEHYDE, WATER NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2002-04-23 US disclosed
US-20010009937-A1 Water-resistant, viscosity stable, alkaline corrugating adhesive composition Henkel IP & Holding GmbH (DE) 2001-07-26 US disclosed
US-6255369-B1 CURABLE AQUEOUS MIXTURE OF STARCH, A BASE, AND A CURING AGENT COMPRISING A KETONE-FORMALDEHYDE CONDENSATE WHICH HAS BEEN TREATED WITH ALKALINE OR ALKALINE EARTH SULFITES TO ELIMINATE FREE FORMALDEHYDE NATIONAL STARCH & CHEMICAL INVESTMENT HOLDING CORPORATION 2001-07-03 US disclosed
EP-0832906-B1 Water resistant alkaline corrugating adhesive composition NAT STARCH CHEM INVEST (US) 2001-06-20 EP disclosed
EP-0672693-B1 Aldehyde resins with reduced and stabilized free-formaldehyde content NAT STARCH CHEM INVEST (US) 2001-06-06 EP disclosed
EP-0627478-B1 All natural, starch-based, water resistant corrugating adhesive NAT STARCH CHEM INVEST (US) 1998-10-21 EP disclosed
EP-0849342-A1 All natural, starch-based, water-resistant corrugating adhesive NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1998-06-24 EP disclosed
EP-0832906-A2 Water resistant alkaline corrugating adhesive composition National Starch and Chemical Investment Holding Corporation (US) 1998-04-01 EP disclosed
US-4400480-A ADHESIVE OF STARCH AND ACETONE-FORMALDEHYDE RESIN NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1983-08-23 US disclosed
US-4366275-A CROSSLINKING ADDITIVE COMPRISING AN ACETONE-FORMALDEHYDE CONDENSATE OF STARCHES NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1982-12-28 US disclosed
EP-0066056-A1 Improved crosslinking additive for water-resistant alkaline corrugating adhesive composition National Starch and Chemical Corporation (US) 1982-12-08 EP disclosed
US-4112036-A THERMOSETTING POLYESTER RESINS CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1978-09-05 US disclosed
US-4033921-A ADHESIVES, COATINGS THE LUBRIZOL CORPORATION (US) 1977-07-05 US disclosed
US-4026856-A Adhesives prepared from alkaline reagents and polymers of water-soluble hydroxyalkylated and alkoxyalkylated compositions and the like derived from N-3-oxohydrocarbon-substituted acrylamides THE LUBRIZOL CORPORATION (US) 1977-05-31 US disclosed
US-3968791-A Orthopedic bandage comprising diacetone acrylamide, and cast prepared therefrom THE LUBRIZOL CORPORATION (US) 1976-07-13 US disclosed
US-3961961-A POSITIVE OR NEGATIVE DEVELOPABLE PHOTOSENSITIVE COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-06-08 US disclosed
US-3959224-A Water-soluble hydroxyalkylated and alkoxyalkylated compositions and the like derived from N-3-oxohydrocarbon-substituted acrylamides, and polymers thereof THE LUBRIZOL CORPORATION (US) 1976-05-25 US disclosed
US-3944428-A Alkaline curing corrugating adhesive NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1976-03-16 US disclosed