Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749882 | 0.95 | HPGD (0.54) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| SCHEMBL7059270 | 0.88 | HPGD (0.62) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| SCHEMBL8979405 | 0.88 | HPGD (0.62) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| SCHEMBL4359815 | 0.88 | MAPT (0.63) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| SCHEMBL1653792 | 0.80 | GPR35 (0.49) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8749857 | 0.80 | KAT2B (0.47) | MAPTMEN1KMT2ATDP1KAT2B | |
| SCHEMBL8869597 | 0.80 | KAT2B (0.49) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL9225184 | 0.79 | KAT2B (0.48) | KAT2BALDH1A1HCAR3PRSS1 | |
| SCHEMBL11412694 | 0.79 | KAT2B (0.43) | HPGDTHRBL3MBTL1MAPTMEN1 | |
| SCHEMBL29183738 | 0.79 | TSHR (0.52) | MAPTMEN1KMT2ATDP1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614368-A | LABELLED-HAPTEN WITH POLYPEPTIDES FOR DIAGNOSIS OF ANTIGENS AND ANTIBODIES | MOLECULAR DEVICES CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5258507-A | FOR IN SITU DETECTION OF NUCLEIC ACID SEQUENCES | AMOCO CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |
| US-5180828-A | Proteins and polynucleotides, nondestructive | MOLECULAR DEVICES CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0485155-A1 | Novel labeling reagents useful for the chemical attachment of nitrophenyl derivative ligands to DNA probes | AMOCO CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |