Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026709 | 0.88 | KAT2B (0.60) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL6198359 | 0.88 | KAT2B (0.78) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL8720672 | 0.88 | KAT2B (0.78) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL8868809 | 0.88 | HPGD (0.58) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL6200169 | 0.86 | KAT2B (0.81) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL5668940 | 0.84 | RAB9A (0.55) | MAPTKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL7170020 | 0.83 | KAT2B (0.81) | MAPTKMT2AMEN1TDP1KAT2B | |
| SCHEMBL37830 | 0.82 | MAPT (0.63) | MAPTKMT2AMEN1TDP1HPGD | |
| SCHEMBL29928397 | 0.82 | MAPT (0.63) | MAPTKMT2AMEN1TDP1HPGD | |
| SCHEMBL4295085 | 0.82 | MAPT (0.63) | MAPTKMT2AMEN1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071444-A9 | NOVEL IMAGING METHOD | GE HEALTHCARE LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |