Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870231 | 0.96 | CA2 (0.47) | P4HTMPOLBEGFRCA2MMP1 | |
| SCHEMBL8868007 | 0.94 | P4HTM (0.47) | P4HTMPOLBEGFRCA2TDP1 | |
| SCHEMBL8868067 | 0.93 | HPGD (0.44) | P4HTMPOLBEGFRTDP1MEN1 | |
| SCHEMBL8868717 | 0.93 | P4HTM (0.48) | P4HTMPOLBEGFRCA2MMP1 | |
| SCHEMBL8867726 | 0.92 | P4HTM (0.48) | P4HTMPOLBEGFRCA2MMP1 | |
| SCHEMBL8868634 | 0.92 | P4HTM (0.51) | P4HTMEGFRCA2MMP1TDP1 | |
| SCHEMBL8869141 | 0.91 | P4HTM (0.45) | P4HTMPOLBEGFRCA2TDP1 | |
| SCHEMBL8869197 | 0.91 | NPC1 (0.46) | P4HTMCA2MEN1KMT2AMAPT | |
| SCHEMBL8869529 | 0.90 | CA2 (0.48) | P4HTMPOLBEGFRCA2TDP1 | |
| SCHEMBL8867435 | 0.90 | NPC1 (0.46) | P4HTMCA2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |