Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867612 | 0.97 | P4HTM (0.53) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL8868785 | 0.93 | P4HTM (0.55) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL8869377 | 0.90 | P4HTM (0.56) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL8869186 | 0.87 | P4HTM (0.69) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL9136785 | 0.87 | P4HTM (0.57) | P4HTMPTPN1 | |
| SCHEMBL8869702 | 0.87 | P4HTM (0.57) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL7869446 | 0.87 | GABRA5 (0.45) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8869591 | 0.86 | P4HTM (0.56) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 | |
| SCHEMBL8867934 | 0.86 | GABRA5 (0.46) | P4HTMHPGDPTPN1ALDH1A1MAPT | |
| SCHEMBL8867998 | 0.85 | P4HTM (0.51) | P4HTMNPC1RAB9AHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |