Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869834 | 0.94 | P4HTM (0.48) | PPARASMN1; SMN2ALDH1A1LMNAHIF1A | |
| SCHEMBL8867299 | 0.92 | CA1 (0.43) | PPARASMN1; SMN2ALDH1A1LMNANAMPT | |
| SCHEMBL8869533 | 0.92 | PPARA (0.49) | PPARASMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8868797 | 0.91 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2ALDH1A1LMNANAMPT | |
| SCHEMBL8868856 | 0.91 | CA1 (0.51) | PPARASMN1; SMN2ALDH1A1LMNACA1 | |
| SCHEMBL8869629 | 0.91 | P4HTM (0.45) | PPARASMN1; SMN2ALDH1A1LMNAHIF1A | |
| SCHEMBL8867910 | 0.90 | NLRP3 (0.54) | SMN1; SMN2ALDH1A1LMNANAMPTHIF1A | |
| SCHEMBL8869698 | 0.90 | PPARA (0.53) | PPARASMN1; SMN2ALDH1A1LMNANAMPT | |
| SCHEMBL8869066 | 0.90 | PPARA (0.53) | PPARASMN1; SMN2ALDH1A1LMNANAMPT | |
| SCHEMBL8868570 | 0.89 | HIF1A (0.48) | PPARASMN1; SMN2ALDH1A1LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |