Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464649 | 0.83 | KMT2A (0.40) | MEN1KMT2AFDPSLPOTSHR | |
| SCHEMBL1044189 | 0.80 | KMT2A (0.54) | MEN1KMT2AFDPSGABRA1GABRG2 | |
| SCHEMBL27475942 | 0.79 | MEN1 (0.41) | MEN1KMT2AFDPSLPOTSHR | |
| Hydrochloric Acid SCHEMBL1875423 | 0.79 | KMT2A (0.53) | MEN1KMT2AFDPSGABRA1GABRG2 | |
| Ethylene SCHEMBL28111857 | 0.77 | KMT2A (0.51) | MEN1KMT2AFDPSGABRA1GABRG2 | |
| SCHEMBL4063363 | 0.77 | FDPS (0.48) | MEN1KMT2AFDPSLPOTSHR | |
| Ethylene SCHEMBL28201781 | 0.76 | KMT2A (0.50) | MEN1KMT2AFDPSGABRA1GABRG2 | |
| SCHEMBL21721828 | 0.75 | HTR1D (0.43) | MEN1KMT2AFDPSTSHROPRK1 | |
| SCHEMBL863744 | 0.75 | MEN1 (0.61) | MEN1KMT2AFDPSLPOTSHR | |
| SCHEMBL1044399 | 0.72 | NR4A1 (0.46) | MEN1KMT2AFDPSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |