Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869448 | 0.83 | MEN1 (0.41) | KMT2AMEN1FDPSADORA2BLPO | |
| SCHEMBL3401058 | 0.82 | KMT2A (0.53) | KMT2AMEN1ADORA2BNPC1POLB | |
| SCHEMBL7154948 | 0.81 | FDPS (0.48) | KMT2AMEN1FDPSLPOCNR2 | |
| Bromide SCHEMBL29657458 | 0.79 | FDPS (0.47) | KMT2AMEN1FDPSLPOCNR2 | |
| SCHEMBL7444527 | 0.79 | KCNJ1 (0.46) | KMT2AMEN1TSHRHSD17B10 | |
| Water SCHEMBL29120398 | 0.75 | FDPS (0.44) | KMT2AMEN1FDPSLPOCNR2 | |
| SCHEMBL863744 | 0.75 | MEN1 (0.61) | KMT2AMEN1FDPSLPOTSHR | |
| SCHEMBL1474745 | 0.74 | TBXAS1 (0.49) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL16700858 | 0.73 | KMT2A (0.48) | KMT2AMEN1FDPSADORA2BCNR2 | |
| SCHEMBL7167511 | 0.73 | PRSS1 (0.42) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |