Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869674 | 1.00 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20495063 | 0.80 | MEN1 (0.59) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20511418 | 0.80 | MEN1 (0.62) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL513724 | 0.80 | MEN1 (0.56) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| Potassium Ion SCHEMBL11364976 | 0.77 | TSHR (0.40) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11349513 | 0.77 | TSHR (0.40) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11706825 | 0.77 | KMT2A (0.42) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL515116 | 0.76 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28072452 | 0.75 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1252918 | 0.75 | KMT2A (0.64) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606066-A | Light activable \"caged\" 1-(2-nitrobenzyl)-substituted 1,4-dihydropyridines | GOLDMANN SIEGFRIED (DE) | 1997-02-25 | — | — | US | disclosed |
| EP-0650477-A1 | LIGHT-ACTIVABLE 1-(2-NITROBENZYL)-SUBSTITUTED 1,4-DIHYDROPYRIDINES | GOLDMANN, Siegfried (DE) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001405-A1 | LIGHT-ACTIVABLE 1-(2-NITROBENZYL)-SUBSTITUTED 1,4-DIHYDROPYRIDINES | GOLDMANN SIEGFRIED (DE) | 1994-01-20 | — | — | WO | disclosed |